Oxford Covid-19 vaccine questions and answers: How does it work and how is it different from Pfizer vaccine?

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Where is it made?

While some doses will come from Europe initially, the majority will come from the UK supply chain.

In an exclusive report on January 16, The telegraph shared plans for a new £ 158million ‘super-factory’ that would produce 70million doses of an emergency vaccine on UK soil – enough to vaccinate the entire nation against new strains of coronavirus in every four months. The factory will open later this year.

Do you need two doses of the Oxford vaccine?

The MHRA has recommended that those over 18 receive two doses to be administered four to 12 weeks apart.

When will I get my second dose?

The government announced on December 30 that it was delaying the second dose of each vaccine in order to reach as many people as possible during the first round of vaccinations.

Both the Oxford vaccine and the Pfizer / BioNTech vaccine will be given to people as a single injection, followed by another up to 12 weeks later, in order to extend some protection to as many people as possible as quickly as possible.

This is not without controversy, however.

The Government’s Joint Committee on Vaccination and Immunization (JCVI) said unpublished data suggests the Oxford-AstraZeneca vaccine is still effective with doses 12 weeks apart – but Pfizer said it didn’t had only tested the effectiveness of his vaccine when the two doses had been given for up to 21 days. a part.

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The World Health Organization has recommended a four-week interval between doses – to be extended only in exceptional circumstances to six weeks.

Will vaccines be distributed 24 hours a day?

In a new attempt to speed up vaccination, Boris Johnson has announced that 24-hour vaccination centers will be opened “as soon as possible”, with the head of NHS England confirming on January 17 that several hospitals will test 24-hour vaccination centers on 24, 7 days a week. in the next ten days.

Matt Hancock, however, told TBEN Breakfast that a 24/7 approach was unlikely to be “the major factor” in reaching the mid-February target, but he was “absolutely” behind. if that helped speed things up. ”

Sources in Whitehall said plans are in place to pilot a 24-hour vaccination center to test demand. It comes as manufacturing companies have told ministers they would not yet be able to produce enough vaccines if a 24-hour rollout was put in place across the country.

Delivering vaccines overnight will speed up the rollout and allow the government to meet its goal of vaccinating 32 million people – 60% of Britain’s adult population by spring – announced on January 11.

Can this vaccine help the elderly?

There are concerns that a Covid-19 vaccine may not work as well on the elderly, as does the annual flu shot.

However, data from the Oxford / AstraZeneca trial suggests that there were “similar” immune responses in younger and older adults.

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The results show that the vaccine is better tolerated in older people than in young adults and produces a similar immune response in older and younger adults.

Can pregnant women get vaccinated?

Pregnant women and nursing mothers have now been given the green light to take the Oxford and Pfizer coronavirus vaccines after an appropriate risk assessment on a case-by-case basis with their healthcare professional.

This is a reversal of previous opinions which had been put in place as a precautionary measure.

Traditionally, pregnant women have not been included in clinical trials, but following a review, the MHRA recommends that pregnant women be given the option of receiving the vaccine as there is no evidence that they would be risk.

Dr June Raine, Executive Director of the MHRA, said: “Our advice to date has been that, given that, due to the lack of initial evidence on a precautionary basis, the use of a vaccine was not recommended. during pregnancy and lactating women should not be administered the vaccine.

“But now that we have reviewed other data that has become available, the Commission for Medicinal Products for Human Use has indicated that the vaccine may be considered for use during pregnancy when the potential benefits outweigh the risks after discussion. individual with each woman. “

Can people with allergies be vaccinated?

The Pfizer vaccine rollout has been temporarily halted for people known to suffer from severe allergic reactions following a few adverse events during the initial vaccine distribution.

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There were concerns that this would also apply to the Oxford jab.

However, following a review, the UK regulatory body recommended that Pfizer and Oxford vaccines be safe to give to people with food or medical allergies.

Only those with a known history of vaccine reactions in the past should proceed with caution.

Sir Munir Pirmohamed, clinical pharmacologist and geneticist, and chair of the Commission expert working group on human medicine, said. “We came to the recommendation that people with a known history of reaction to specific ingredients in the vaccine should not have them. But people who are allergic to other drugs or foods can receive the vaccine.”

Dr June Raine added that “at least 800,000 people in the UK, probably 1.5 million in the US” have already received the Pfizer vaccine.

There was “no additional concern and this gives us additional assurance that the risk of anaphylaxis can be managed with standard clinical guidelines and a post-vaccination observation period of at least 15 minutes.

Learn more: The priority list for the Oxford and Pfizer vaccines – and how they will be deployed

Have you received the Covid vaccine or should you receive one? We want to hear from you. Contact us here.

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